College football’s opening weekend starts with one game between ranked teams.

No. 24 Louisville faces No. 9 Mississippi on Sunday night.

Many top teams begin with new coaches and high hopes.

Eligibility disputes and jersey patches add to the intrigue.

Clemson plays No. 11 LSU on Saturday night in a showcase game.

Both teams finished 7-6 last season and want to return to title contention.

LSU’s new coach Lane Kiffin and Clemson’s Dabo Swinney are outspoken leaders.

The game gained extra meaning after new NCAA eligibility rules led to court battles.

LSU sought to bring back players who had signed NFL contracts, and the SEC fought LSU in multiple courtrooms late into the week.

Week 1 lacks many marquee matchups, so lopsided scores are likely.

No. 1 Ohio State is favored by more than 50 points against Ball State.

No. 6 Indiana, No. 8 Texas A&M, and No. 10 Oklahoma are each picked to win by over 40.

Still, upsets happen.

UMass, winless last season, beat Rutgers 37-21 as a big underdog.

Colorado also blocked a field goal to edge Georgia Tech 14-13.

Notre Dame’s CJ Carr and Texas’s Arch Manning lead Heisman preseason talk.

Carr faces Wisconsin on Sunday night, while Manning plays Texas State.

No. 2 Oregon hosts Boise State.

Other games include Auburn vs. Baylor and Tulane at Duke.

The weekend runs Thursday through Monday, with the next AP Top 25 rankings due Tuesday.